{"product_id":"spp1-antibody-cat-csb-pa827743","title":"SPP1 Antibody - Cat. #: CSB-PA827743","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:BNSP antibody; Bone sialoprotein 1 antibody; Bone sialoprotein I antibody; BSP I antibody; BSPI antibody; Early T lymphocyte activation 1 antibody; ETA 1 antibody; ETA1 antibody; MGC110940 antibody; Nephropontin antibody; OPN antibody; Osteopontin antibody; osteopontin\/immunoglobulin alpha 1 heavy chain constant region fusion protein antibody; OSTP_HUMAN antibody; PSEC0156 antibody; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1) antibody; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) antibody; Secreted phosphoprotein 1 antibody; SPP 1 antibody; SPP-1 antibody; SPP1 antibody; SPP1\/CALPHA1 fusion antibody; Urinary stone protein antibody; Uropontin antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P10451\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from Human osteopontin .\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity By similarity.\u003cbr\u003e\u003cbr\u003eGeorge R. Beck, J. Biol. Chem., Oct 2003; 278: 41921 - 41929. \u003cbr\u003eKELLY L. HUDKINS, J. Am. Soc. Nephrol., Mar 1999; 10: 444. \u003cbr\u003eL?a R. Rodrigues, Cancer Epidemiol. Biomarkers Prev., Jun 2007; 16: 1087 - 1097. \u003cbr\u003eYu-Hua Hsieh, Cancer Res., Jul 2006; 66: 7119 - \n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:SPP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer?Cardiovascular;Signal transduction?Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483792879716,"sku":"CSB-PA827743","price":110100.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_9bafc579-d7cc-4db3-a40a-ea1993a5017b.jpg?v=1660076402","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/spp1-antibody-cat-csb-pa827743","provider":"GeneBio ","version":"1.0","type":"link"}