{"product_id":"recombinant-human-lymphotactin-proteinxcl1-active","title":"Recombinant Human Lymphotactin protein(XCL1) (Active)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug. Other sizes are also available. Please contact us. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot NO.\u003c\/b\u003e:P47992\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot Entry Name\u003c\/b\u003e:XCL1_HUMAN\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene Names\u003c\/b\u003e:XCL1,LTN,SCYC1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSource\u003c\/b\u003e:E.Coli\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression Region\u003c\/b\u003e:23-114aa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSequence\u003c\/b\u003e:GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein Description\u003c\/b\u003e:Partial\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTag Info\u003c\/b\u003e:Tag-Free\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMol. Weight\u003c\/b\u003e:10.2 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBiological_Activity\u003c\/b\u003e:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng\/ml.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;98% as determined by SDS-PAGE and HPLC.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e:Less than 1.0 EU\/µg as determined by LAL method.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Lyophilized powder\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Lyophilized from a  0.2 µm filtered  PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReconstitution\u003c\/b\u003e:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg\/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?\/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNotes\u003c\/b\u003e:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlternative Name\/ Alias\u003c\/b\u003e:ATAC, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRelevance\u003c\/b\u003e:Chemotactic activity for lymphocytes but not for monocytes or neutrophils.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePubMed ID\u003c\/b\u003e:7602097; 7875320; 7615002; 8849694; 16710414; 15489334; 11601972\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFunction\u003c\/b\u003e:Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eInvolvement in disease\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSubcellular Location\u003c\/b\u003e:Secreted\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein Families\u003c\/b\u003e:Intercrine gamma family\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTissue Specificity\u003c\/b\u003e:Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePaythway\u003c\/b\u003e:Chemokinesignalingpathway\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHGNC Database Link\u003c\/b\u003e:https:\/\/www.genenames.org\/cgi-bin\/gene_symbol_report?hgnc_id=HGNC:10645\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniGene Database Link\u003c\/b\u003e:https:\/\/www.ncbi.nlm.nih.gov\/UniGene\/clust.cgi?ORG=Hs\u0026amp;CID=458346\u003c\/p\u003e\u003cp\u003e\u003cb\u003eKEGG Database Link\u003c\/b\u003e:https:\/\/www.genome.jp\/dbget-bin\/www_bget?hsa:6375\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSTRING Database Link\u003c\/b\u003e:https:\/\/string-db.org\/network\/9606.ENSP00000356792\u003c\/p\u003e\u003cp\u003e\u003cb\u003eOMIM Database Link\u003c\/b\u003e:https:\/\/www.omim.org\/entry\/600250600250600250\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40529894965348,"sku":"CSB-AP000791HU","price":208000.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_bd7f3ef0-5f29-45df-9375-e1d0c4e1ac27.jpg?v=1661105687","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/recombinant-human-lymphotactin-proteinxcl1-active","provider":"GeneBio ","version":"1.0","type":"link"}