{"product_id":"recombinant-human-beta-defensin-104-proteindefb104a-active","title":"Recombinant Human Beta-defensin 104 protein(DEFB104A) (Active)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug. Other sizes are also available. Please contact us. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Microbiology\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot NO.\u003c\/b\u003e:Q8WTQ1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot Entry Name\u003c\/b\u003e:D104A_HUMAN\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene Names\u003c\/b\u003e:DEFB104A,DEFB104,DEFB4;,DEFB104B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSource\u003c\/b\u003e:E.Coli\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression Region\u003c\/b\u003e:23-72aa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSequence\u003c\/b\u003e:EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein Description\u003c\/b\u003e:Full Length of Mature Protein\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTag Info\u003c\/b\u003e:Tag-Free\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMol. Weight\u003c\/b\u003e:6.0 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBiological_Activity\u003c\/b\u003e:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 0.1-100.0 ng\/ml.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;98% as determined by SDS-PAGE and HPLC.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e:Less than 1.0 EU\/µg as determined by LAL method.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Lyophilized powder\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Lyophilized from a  0.2 µm filtered  20 mM PB, pH 7.4, 130 mM NaCl\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReconstitution\u003c\/b\u003e:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg\/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?\/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNotes\u003c\/b\u003e:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlternative Name\/ Alias\u003c\/b\u003e:Beta-defensin 4, DEFB-4, hBD-4, Defensin, beta 104,\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRelevance\u003c\/b\u003e:Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. {ECO:0000269|PubMed:11481241}.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePubMed ID\u003c\/b\u003e:11481241; 15489334\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFunction\u003c\/b\u003e:Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eInvolvement in disease\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSubcellular Location\u003c\/b\u003e:Secreted\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein Families\u003c\/b\u003e:Beta-defensin family\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTissue Specificity\u003c\/b\u003e:High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested. \u003c\/p\u003e\u003cp\u003e\u003cb\u003ePaythway\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHGNC Database Link\u003c\/b\u003e:https:\/\/www.genenames.org\/cgi-bin\/gene_symbol_report?hgnc_id=HGNC:18115\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniGene Database Link\u003c\/b\u003e:https:\/\/www.ncbi.nlm.nih.gov\/UniGene\/clust.cgi?ORG=Hs\u0026amp;CID=559507\u003c\/p\u003e\u003cp\u003e\u003cb\u003eKEGG Database Link\u003c\/b\u003e:https:\/\/www.genome.jp\/dbget-bin\/www_bget?hsa:107984148\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSTRING Database Link\u003c\/b\u003e:https:\/\/string-db.org\/network\/9606.ENSP00000322191\u003c\/p\u003e\u003cp\u003e\u003cb\u003eOMIM Database Link\u003c\/b\u003e:\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40529903353956,"sku":"CSB-AP003061HU","price":207800.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_4f602ddc-39e4-4925-87c0-8bc464779196.jpg?v=1661105935","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/recombinant-human-beta-defensin-104-proteindefb104a-active","provider":"GeneBio ","version":"1.0","type":"link"}