{"product_id":"pitx2-antibody-cat-csb-pa264237","title":"PITX2 Antibody - Cat. #: CSB-PA264237","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:All1 responsive gene 1 antibody; ALL1 responsive protein ARP1 antibody; ALL1-responsive protein ARP1 antibody; ARP 1 antibody; ARP1 antibody; Brx 1 antibody; Brx1 antibody; Homeobox protein PITX2 antibody; IDG 2 antibody; IDG2 antibody; IGDS 2 antibody; IGDS antibody; IGDS2 antibody; IHG 2 antibody; IHG2 antibody; IRID 2 antibody; IRID2 antibody; MGC111022 antibody; MGC20144 antibody; Otlx 2 antibody; Otlx2 antibody; Paired like homeodomain transcription factor 2 antibody; Paired-like homeodomain transcription factor 2 antibody; Pituitary homeo box 2 antibody; Pituitary homeobox 2 antibody; PITX 2 antibody; pitx2 antibody; PITX2_HUMAN antibody; PTX 2 antibody; PTX2 antibody; RGS antibody; RIEG 1 antibody; RIEG antibody; Rieg bicoid related homeobox transcription factor 1 antibody; RIEG bicoid related homeobox transcription factor antibody; RIEG bicoid-related homeobox transcription factor antibody; RIEG1 antibody; RS antibody; Solurshin antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q99697\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human PITX2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a member of the RIEG\/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PITX2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cardiovascular;Developmental biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482862497892,"sku":"CSB-PA264237","price":61500.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_09e05b16-b12e-4815-bd3f-4400000070c9.jpg?v=1660058287","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/pitx2-antibody-cat-csb-pa264237","provider":"GeneBio ","version":"1.0","type":"link"}