{"product_id":"phospho-ywhaz-ser58-antibody-cat-csb-pa887076","title":"Phospho-YWHAZ (Ser58) Antibody - Cat. #: CSB-PA887076","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:14 3 3 delta antibody; 14 3 3 protein zeta\/delta antibody; 14 3 3 protein\/cytosolic phospholipase A2 antibody; 14 3 3 zeta antibody; 14-3-3 protein zeta\/delta antibody; 1433Z_HUMAN antibody; Epididymis luminal protein 4 antibody; Epididymis secretory protein Li 3 antibody; HEL S 3 antibody; HEL4 antibody; KCIP-1 antibody; KCIP1 antibody; MGC111427 antibody; MGC126532 antibody; MGC138156 antibody; Phospholipase A2 antibody; Protein kinase C inhibitor protein 1 antibody; Tyrosine 3 monooxygenase\/tryptophan 5 monooxygenase activation protein; delta polypeptide antibody; Tyrosine 3 monooxygenase\/tryptophan 5 monooxygenase activation protein; zeta antibody; Tyrosine 3 monooxygenase\/tryptophan 5 monooxygenase activation protein; zeta polypeptide antibody; Tyrosine 3\/tryptophan 5  monooxygenase activation protein; zeta polypeptide antibody; YWHAD antibody; YWHAZ antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P63104\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of serine 58 (R-S-S(p)-W-R) derived from Human 14-3-3 zeta.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.\u003cbr\u003e\u003cbr\u003eGu YM, et al. (2006) FEBS Lett ; 580(1): 305-310\u003cbr\u003ePowell DW, et al. (2003) Mol Cell Biol; 23(15): 5376-5387\u003cbr\u003eMackintosh C. (2004) Biochem J; 381(Pt 2): 329-342.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:YWHAZ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience;Cell biology;Tags \u0026amp; Cell Markers;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484050501732,"sku":"CSB-PA887076","price":133700.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_768f4912-2df9-4bc6-a7c0-dff0d9b85797.jpg?v=1660087012","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/phospho-ywhaz-ser58-antibody-cat-csb-pa887076","provider":"GeneBio ","version":"1.0","type":"link"}