{"product_id":"phospho-marcks-ser170-antibody-cat-csb-pa116247","title":"Phospho-MARCKS (Ser170) Antibody - Cat. #: CSB-PA116247","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:80 kDa protein antibody; 80K L antibody; 80K L protein antibody; 80K-L protein antibody; 80KL antibody; 81 kDa protein; light chain antibody; light chain antibody; MACS antibody; MARCKS antibody; MARCS antibody; MARCS_HUMAN antibody; MGC52672 antibody; myristoylated alanine rich C kinase substrate antibody; Myristoylated alanine rich protein kinase C substrate (MARCKS; 80K L) antibody; Myristoylated alanine rich protein kinase C substrate antibody; Myristoylated alanine-rich C-kinase substrate antibody; Phosphomyristin antibody; PKCSL antibody; PRKCSL antibody; protein kinase C substrate 80 kDa protein light chain antibody; Protein kinase C substrate antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P29966\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of Serine 170 (G-F-S(p)-F-K) derived from Human MARCKS.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eMARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.  \u003cbr\u003e\u003cbr\u003eRamsden, J.J. (2000) Int. J. Biochem. Cell Biol. 32, 475-479. \u003cbr\u003eGraff, J. M. et al. (1989) J. Biol. Chem. 264, 21818-21823. \u003cbr\u003eHartwig, J. H. et al. (1992) Nature 356, 618-622. \u003cbr\u003eThelen, M. et al. (1991) Nature 351, 320-322.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:MARCKS\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cardiovascular;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484052074596,"sku":"CSB-PA116247","price":133500.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_1290e550-0836-48c5-bc38-28fa2d3f3a3c.jpg?v=1660087062","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/phospho-marcks-ser170-antibody-cat-csb-pa116247","provider":"GeneBio ","version":"1.0","type":"link"}