{"product_id":"phospho-ccnd1-ser90-antibody-cat-csb-pa963558","title":"Phospho-CCND1 (Ser90) Antibody - Cat. #: CSB-PA963558","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AI327039 antibody; B cell CLL\/lymphoma 1 antibody; B cell leukemia 1 antibody; B cell lymphoma 1 protein antibody; B-cell lymphoma 1 protein antibody; BCL 1 antibody; BCL-1 antibody; BCL-1 oncogene antibody; BCL1 antibody; BCL1 oncogene antibody; ccnd1 antibody; CCND1\/FSTL3 fusion gene antibody; CCND1\/FSTL3 fusion gene; included antibody; CCND1\/IGHG1 fusion gene antibody; CCND1\/IGHG1 fusion gene; included antibody; CCND1\/IGLC1 fusion gene antibody; CCND1\/IGLC1 fusion gene; included antibody; CCND1\/PTH fusion gene antibody; CCND1\/PTH fusion gene; included antibody; CCND1_HUMAN antibody; cD1 antibody; Cyl 1 antibody; D11S287E antibody; G1\/S specific cyclin D1 antibody; G1\/S-specific cyclin-D1 antibody; Parathyroid adenomatosis 1 antibody; PRAD1 antibody; PRAD1 oncogene antibody; U21B31 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P24385\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of serine 90(F-L-S(p)-L-E) derived from Human Cyclin D1 .\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eAccepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6\/E6-AP-induced ubiquitination of p53\/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63\/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.\u003cbr\u003e\u003cbr\u003eSewing A, M?er R (1994) Oncogene 9, 2733-6\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CCND1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484028022884,"sku":"CSB-PA963558","price":133500.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_8f102126-2d79-4431-a37a-dec1b6d9f75a.jpg?v=1660086397","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/phospho-ccnd1-ser90-antibody-cat-csb-pa963558","provider":"GeneBio ","version":"1.0","type":"link"}