{"product_id":"lc3a-rabbit-polyclonal-antibody-ab","title":"LC3A Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100μL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Probably involved in formation of autophagosomal vacuoles (autophagosomes).|PTM:The precursor molecule is cleaved by APG4B\/ATG4B to form the cytosolic form| LC3-I. This is activated by APG7L\/ATG7| transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form| LC3-II.|Belongs to the MAP1 LC3 family.|subcellular location:LC3-II binds to the autophagic membranes.|subunit:3 different light chains| LC1| LC2 and LC3| can associate with MAP1A and MAP1B proteins.|tissue specificity:Most abundant in heart| brain| liver| skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.|\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch_area\u003c\/b\u003e:Cancer; Cardiovascular; Metabolism; Neuroscience; Signal transduction\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget_protein\u003c\/b\u003e:MAP1LC3A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eapplications\u003c\/b\u003e:WB,  ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e:Human, Rat, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene Symbol\/ Name\u003c\/b\u003e:LC3A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:-20°C for 1 year\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:1 mg\/ml\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMolecular weight(Da)\u003c\/b\u003e:13310\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt accession\u003c\/b\u003e:Human: Q9H492; Mouse: Q91VR7; Rat: Q6XVN8\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e:LC3A; Microtubule-associated proteins 1A\/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A\/MAP1B light chain 3 A; MAP1A\/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGeneID\u003c\/b\u003e:Human: 84557; Mouse: 66734; Rat: 362245\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48650219618404,"sku":"BT-AP11013","price":87100.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_91f276eb-7406-4d32-aecc-9dc5c13dfd9f.jpg?v=1782730371","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/lc3a-rabbit-polyclonal-antibody-ab","provider":"GeneBio ","version":"1.0","type":"link"}