{"product_id":"kdm1b-antibody-cat-csb-pa822748la01hu","title":"KDM1B Antibody - Cat. #: CSB-PA822748LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:amine oxidase (flavin containing) domain 1 antibody; amine oxidase, flavin containing 1 antibody; AOF1 antibody; bA204B7.3 antibody; C6orf193 antibody; dJ298J15.2 antibody; Flavin-containing amine oxidase domain-containing protein 1 antibody; FLJ33898 antibody; FLJ34109 antibody; FLJ43328 antibody; KDM1B antibody; KDM1B_HUMAN antibody; LSD2 antibody; lysine (K)-specific demethylase 1B antibody; Lysine-specific demethylase 2 antibody; Lysine-specific histone demethylase 1B antibody; Lysine-specific histone demethylase 2 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q8NB78\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Lysine-specific histone demethylase 1B protein (451-544AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; Recommended dilution: IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Histone demethylase that demethylates \\'Lys-4\\' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated \\'Lys-4\\' of histone H3. Has no effect on tri-methylated \\'Lys-4\\', mono-, di- or tri-methylated \\'Lys-9\\', mono-, di- or tri-methylated \\'Lys-27\\', mono-, di- or tri-methylated \\'Lys-36\\' of histone H3, or on mono-, di- or tri-methylated \\'Lys-20\\' of histone H4 (By similarity).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KDM1B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486369951844,"sku":"CSB-PA822748LA01HU","price":61600.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_da7f0557-9787-4867-a111-7714e3cb96f4.jpg?v=1660145706","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/kdm1b-antibody-cat-csb-pa822748la01hu","provider":"GeneBio ","version":"1.0","type":"link"}