{"product_id":"ifit2-antibody-cat-csb-pa011021la01hu","title":"IFIT2 Antibody - Cat. #: CSB-PA011021LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:CIG-42 antibody; cig42 antibody; G10P2 antibody; GARG 39 antibody; Glucocorticoid attenuated response gene 39 antibody; IFI 54 antibody; IFI 54K antibody; IFI-54K antibody; IFI54 antibody; IFIT 2 antibody; IFIT-2 antibody; IFIT2 antibody; IFIT2_HUMAN antibody; Interferon induced 54 kDa protein antibody; Interferon induced protein 54 antibody; Interferon induced protein with tetratricopeptide repeats 2 antibody; Interferon, alpha inducible protein (MW 54kD) antibody; Interferon-induced 54 kDa protein antibody; Interferon-induced protein with tetratricopeptide repeats 2 antibody; ISG 54 K antibody; ISG 54K antibody; ISG-54 K antibody; ISG54 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P09913\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2\\\\\\'-O-methylation of the 5\\\\\\' cap. The ribose 2\\\\\\'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2\\\\\\'-O-methylase for their mRNAs or by stealing host cap containing the 2\\\\\\'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5\\\\\\' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:IFIT2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486811467876,"sku":"CSB-PA011021LA01HU","price":62000.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_2fb1471d-ab36-4e40-8340-d73841f048c8.jpg?v=1660154024","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/ifit2-antibody-cat-csb-pa011021la01hu","provider":"GeneBio ","version":"1.0","type":"link"}