{"product_id":"gucy1b3-antibody-cat-csb-pa214476","title":"GUCY1B3 Antibody - Cat. #: CSB-PA214476","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:GC-S-beta-1 antibody; GC-SB3 antibody; GCbeta1 antibody; GCS beta 1 antibody; GCS beta 3 antibody; GCS-beta-1 antibody; GCS-beta-3 antibody; GCYB1_HUMAN antibody; guanylate cyclase 1; soluble; beta 3 antibody; Guanylate cyclase soluble beta 1 chain antibody; Guanylate cyclase soluble subunit beta-1 antibody; Guanylate cyclase soluble subunit beta-3 antibody; GUC1B3 antibody; GUCSB3 antibody; GUCY1B1 antibody; Gucy1b1; antibody; GUCY1B3 antibody; SGC antibody; Soluble guanylate cyclase small subunit antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q02153\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from Human Guanylate Cyclase ?.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.\u003cbr\u003e\u003cbr\u003eA. Shimouchi, Am J Physiol Lung Cell Mol Physiol, Nov 1993; 265: 456.\u003cbr\u003ePeter Sinnaeve, Circ. Res., Jan 2001; 88: 103.\u003cbr\u003eStephan Thelitz, J. Thorac. Cardiovasc. Surg., May 2004; 127: 1285 - 1292.\u003cbr\u003eRichard C. Venema, Am J Physiol Heart Circ Physiol, Jul 2003; 2\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:GUCY1B1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483792060516,"sku":"CSB-PA214476","price":110900.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_c9b0ad6b-0e15-4da0-a75d-8a3f84342eae.jpg?v=1660076372","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/gucy1b3-antibody-cat-csb-pa214476","provider":"GeneBio ","version":"1.0","type":"link"}