{"product_id":"caspase-4-activity-detection-substrate-for-flow-cytometry","title":"Caspase 4 Activity Detection Substrate for Flow Cytometry","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100Tests\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:This product can be stored at -20℃ for 1 year in the dark.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:Gel Packs \u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_I\u003c\/b\u003e:Apoptosis and Cell Health Detection\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Cell Apoptosis\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Caspase Assay Kits\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Species\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUsage\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eKit Type\u003c\/b\u003e:Apoptosis\/Caspase\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResult Type\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDetection Instrument\u003c\/b\u003e:Flow Cytometer;Fluorescence microscope\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Sample Types\u003c\/b\u003e:Cell samples\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAssay Time\u003c\/b\u003e:30 min\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDetection Type\u003c\/b\u003e:Fluorometric method;Flow cytometry\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTest Principle\u003c\/b\u003e:The Caspase 4 Activity Detection Substrate for Flow Cytometry are a novel fluorogenic dye that couple the caspase 4 recognition sequence (LEVD) to a high affinity DNA dye, which have cell membrane permeability and can penetrate the plasma membrane into the cytoplasm. The substrate itself has no fluorescence and has a charge exclusion effect with DNA. During cell apoptosis, caspase-4 cleaves the substrate and releases high affinity DNA dyes, which bind to DNA to produce strong fluorescence, thereby detecting caspase-4 activity and visualizing the morphological changes of the cell nucleus during apoptosis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBinding Capacity\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReconstitution\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCalculated MW\u003c\/b\u003e:\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48665606193252,"sku":"E-CK-A484","price":127200.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_6944a8d0-6aad-4406-a27b-38f995f80351.jpg?v=1782866836","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/caspase-4-activity-detection-substrate-for-flow-cytometry","provider":"GeneBio ","version":"1.0","type":"link"}