{"product_id":"bcar1-ab-410-antibody-cat-csb-pa094765","title":"BCAR1 (Ab-410) Antibody - Cat. #: CSB-PA094765","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:BCAR 1 antibody; Bcar1 antibody; BCAR1_HUMAN antibody; Breast cancer anti estrogen resistance 1 antibody; Breast cancer anti estrogen resistance 1 protein antibody; Breast cancer anti-estrogen resistance protein 1 antibody; CAS antibody; Cas scaffolding protein family member 1 antibody; CAS1 antibody; Cass1 antibody; Crk associated substrate antibody; Crk associated substrate p130Cas antibody; CRK-associated substrate antibody; CRKAS antibody; FLJ12176 antibody; FLJ45059 antibody; p130cas antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P56945\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized non-phosphopeptide derived from Human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-T-A-V).\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.\u003cbr\u003e\u003cbr\u003eKatarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535.\u003cbr\u003eKevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863.\u003cbr\u003eSangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189.\u003cbr\u003eNorikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:BCAR1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483997122660,"sku":"CSB-PA094765","price":110900.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_7ead05d6-0cf2-40ae-a4e3-ef4785b6bea0.jpg?v=1660085726","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/bcar1-ab-410-antibody-cat-csb-pa094765","provider":"GeneBio ","version":"1.0","type":"link"}