{"product_id":"anti-human-ms4a1-cd3e-bispecific-reference-antibody-glofitamab-ruo","title":"Anti-Human MS4A1 \u0026 CD3E Bispecific Reference Antibody (Glofitamab, RUO)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDescription\u003c\/b\u003e:Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is an investigational, T-cell bispecific antibody with a distinctive design that features 2 Fab arms for binding CD20 on B cells, along with 1 Fab arm for binding CD3 on T cells. The CD3 binding arm is fused directly to one of the CD20-binding arms in a head-to-tail fashion via a short flexible linker.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost species\u003c\/b\u003e:Humanized\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested applications\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage buffer\u003c\/b\u003e:0.01M PBS, pH 7.4.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;95% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG1-kappa-lambda\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA, Bioactivity: FACS, Functional assay, Research in vivo\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e:B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20, T3E, T-cell surface antigen T3\/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin level\u003c\/b\u003e:Please contact us for this information.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression system\u003c\/b\u003e:Mammalian Cells\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:P11836 \u0026amp; P07766\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStability and Storage\u003c\/b\u003e:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReconstitution\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlternative Names\u003c\/b\u003e:Bispecific, CD20-TCB (2:1), RG-6026, 2229047-91-8\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote\u003c\/b\u003e:For research use only. Not suitable for clinical or therapeutic use.\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48672927973476,"sku":"HY257146","price":57900.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_369b1430-9c49-46ef-b627-be2e64c4d297.jpg?v=1782939158","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/anti-human-ms4a1-cd3e-bispecific-reference-antibody-glofitamab-ruo","provider":"GeneBio ","version":"1.0","type":"link"}