{"product_id":"sycp1-antibody-cat-csb-pa225456","title":"SYCP1 Antibody - Cat. #: CSB-PA225456","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Cancer\/testis antigen 8 antibody; CT8 antibody; HOM TES 14 antibody; MGC104417 antibody; SCP 1 antibody; SCP-1 antibody; SCP1 antibody; SYCP 1 antibody; Sycp1 antibody; SYCP1_HUMAN antibody; Synaptonemal complex protein 1 antibody; Testicular tissue protein Li 191 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q15431\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthetic peptide of Human SYCP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The synaptonemal complex protein 1 (SCP-1), also known as SYCP1(A), SYN1(I) and HOM-TES-14, is a protein product of human chromosome 1p13-p12. SCP-1 is a major component of the transverse filaments of synaptonemal complexes and functions by pairing homologous chromosomes during meiotic prophase in spermatocytes, which is an essential step for the generation of haploid cells in meiosis I. SCP-1 is expressed in the testis, adult brain, some malignant gliomas, breast, renal cell and ovarian cancer. SCP-1 is known to be selectively expressed during the meiotic prophase of spermatocytes and shows cell cycle phase-independent nuclear expression in cancer cells.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:SYCP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483626025060,"sku":"CSB-PA225456","price":287.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_68b74bb4-41a6-4104-a790-fbbf5e7c8bd3.jpg?v=1660072612","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/sycp1-antibody-cat-csb-pa225456","provider":"GeneBio ","version":"1.0","type":"link"}