{"product_id":"srebf1-antibody-cat-csb-pa022657la01hu","title":"SREBF1 Antibody - Cat. #: CSB-PA022657LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:ADD 1 antibody; bHLHd1 antibody; Class D basic helix-loop-helix protein 1 antibody; D630008H06 antibody; Processed sterol regulatory element-binding protein 1 antibody; SRBP1_HUMAN antibody; SREBF 1 antibody; SREBF1 antibody; SREBP 1 antibody; SREBP 1c antibody; SREBP-1 antibody; SREBP1 antibody; Sterol regulatory element binding protein 1 antibody; Sterol Regulatory Element Binding Transcription Factor 1 \/ Protein 1 antibody; Sterol regulatory element binding transcription factor 1 antibody; Sterol regulatory element-binding transcription factor 1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P36956\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Sterol regulatory element-binding protein 1 protein (38-201AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5\\\\\\'-ATCACCCCAC-3\\\\\\'). Has dual sequence specificity binding to both an E-box motif (5\\\\\\'-ATCACGTGA-3\\\\\\') and to SRE-1 (5\\\\\\'-ATCACCCCAC-3\\\\\\').\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:SREBF1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487182729316,"sku":"CSB-PA022657LA01HU","price":287.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_fd1d8c8c-9af1-4cf7-83c3-808d1c9c4c05.jpg?v=1660160410","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/srebf1-antibody-cat-csb-pa022657la01hu","provider":"GeneBio ","version":"1.0","type":"link"}