{"product_id":"skp1-antibody-cat-csb-pa081737","title":"SKP1 Antibody - Cat. #: CSB-PA081737","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Cyclin A\/CDK2 associated p19 antibody; Cyclin A\/CDK2 associated protein p19 antibody; Cyclin-A\/CDK2-associated protein p19 antibody; EMC19 antibody; MGC34403 antibody; OCP 2 antibody; OCP II antibody; OCP II protein antibody; OCP-2 antibody; OCP-II antibody; OCP2 antibody; OCPII antibody; Organ of Corti protein 2 antibody; Organ of Corti protein II antibody; OTTHUMP00000159379 antibody; OTTHUMP00000159380 antibody; OTTHUMP00000228275 antibody; OTTHUMP00000228276 antibody; OTTHUMP00000228278 antibody; OTTHUMP00000228279 antibody; OTTHUMP00000228281 antibody; p19A antibody; p19skp1 antibody; RNA polymerase II elongation factor like protein antibody; RNA polymerase II elongation factor like protein OCP2 antibody; RNA polymerase II elongation factor-like protein antibody; S phase kinase associated protein 1 antibody; S phase kinase associated protein 1A antibody; S phase kinase associated protein 1A p19A antibody; S-phase kinase-associated protein 1 antibody; SIII antibody; Skp 1 antibody; SKP 1A antibody; skp1 antibody; SKP1_HUMAN antibody; SKP1A antibody; TCEB1L antibody; Transcription Elongation Factor B 1 like antibody; Transcription elongation factor B antibody; Transcription elongation factor B SIII polypeptide 1 like antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P63208\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human SKP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:SKP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482815311972,"sku":"CSB-PA081737","price":292.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_24ac9de5-a941-4418-8550-17786c8b033f.jpg?v=1660057313","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/skp1-antibody-cat-csb-pa081737","provider":"GeneBio ","version":"1.0","type":"link"}