{"product_id":"ptpn22-antibody-cat-csb-pa171916","title":"PTPN22 Antibody - Cat. #: CSB-PA171916","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Hematopoietic cell protein tyrosine phosphatase 70Z PEP antibody; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP antibody; Lymphoid phosphatase antibody; Lymphoid specific protein tyrosine phosphatase antibody; lymphoid-specific; inducible human protein tyrosine phosphatase antibody; Lyp 1 antibody; Lyp 2 antibody; LyP antibody; Lyp1 antibody; Lyp2 antibody; LyPTP antibody; OTTHUMP00000013720 antibody; OTTHUMP00000013721 antibody; OTTHUMP00000233450 antibody; OTTHUMP00000233451 antibody; PEP antibody; PEST-domain phosphatase antibody; Protein tyrosine phosphatase non receptor type 22 (lymphoid) antibody; Protein tyrosine phosphatase non receptor type 22 antibody; Protein tyrosine phosphatase non receptor type 8 antibody; Protein tyrosine phosphatase non receptor type 8; formerly antibody; PTN22_HUMAN antibody; PTPN 22 antibody; PTPN 8 antibody; Ptpn22 antibody; PTPN8 antibody; PTPN8; formerly antibody; Tyrosine-protein phosphatase non-receptor type 22 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9Y2R2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human PTPN22\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:30-1:150\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PTPN22\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483269738596,"sku":"CSB-PA171916","price":292.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_bc8597a9-a922-478e-bc4e-83be59f4d280.jpg?v=1660067578","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/ptpn22-antibody-cat-csb-pa171916","provider":"GeneBio ","version":"1.0","type":"link"}