{"product_id":"phospho-tal1-ser122-antibody-cat-csb-pa117607","title":"Phospho-TAL1 (Ser122) Antibody - Cat. #: CSB-PA117607","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:bHLHa17 antibody; Class A basic helix-loop-helix protein 17 antibody; OTTHUMP00000009563 antibody; OTTHUMP00000009564 antibody; SCL antibody; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR antibody; Stem cell protein antibody; T cell acute lymphocytic leukemia 1 antibody; T cell acute lymphocytic leukemia 1 protein antibody; T cell acute lymphocytic leukemia 1 protein antibody; T cell leukemia\/lymphoma 5 protein antibody; T-cell acute lymphocytic leukemia protein 1 antibody; T-cell leukemia\/lymphoma protein 5 antibody; Tal 1 antibody; Tal 1 product antibody; TAL 1 protein antibody; TAL bHLH transcription factor 1 erythroid differentiation factor antibody; TAL-1 antibody; tal1 antibody; TAL1_HUMAN antibody; TCL 5 antibody; TCL5 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P17542\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eTAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2. \u003cbr\u003e\u003cbr\u003eAplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).\u003cbr\u003eGregory S.G., Nature 441:315-321(2006).\u003cbr\u003eChen Q., J. Exp. Med. 172:1403-1408(1990).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:TAL1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Cell biology?Developmental biology;Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484032708708,"sku":"CSB-PA117607","price":621.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_8a180c91-9078-4517-8e4f-05c4f1c95dc0.jpg?v=1660086526","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/phospho-tal1-ser122-antibody-cat-csb-pa117607","provider":"GeneBio ","version":"1.0","type":"link"}