{"product_id":"phospho-nos2-tyr151-antibody-cat-csb-pa178152","title":"Phospho-NOS2 (Tyr151) Antibody - Cat. #: CSB-PA178152","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:HEP-NOS antibody; Hepatocyte NOS antibody; HEPNOS antibody; inducible antibody; Inducible nitric oxide synthase antibody; Inducible NO synthase antibody; Inducible NOS antibody; iNOS antibody; MAC NOS antibody; Macrophage NOS antibody; Nitric oxide synthase 2 inducible antibody; Nitric oxide synthase 2 inducible macrophage antibody; nitric oxide synthase 2A (inducible, hepatocytes) antibody; Nitric oxide synthase antibody; Nitric oxide synthase inducible antibody; nitric oxide synthase, macrophage antibody; NOS 2 antibody; NOS antibody; Nos II antibody; NOS type II antibody; nos2 antibody; NOS2_HUMAN antibody; NOS2A antibody; NOS2A, Inducible, Hepatocyte antibody; Peptidyl-cysteine S-nitrosylase NOS2 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P35228\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of tyrosine 151(Q-Y-Y(p)-G-S) derived from Human  iNOS .\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eProduces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.\u003cbr\u003e\u003cbr\u003eGeller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993).\u003cbr\u003eSherman P.A., Biochemistry 32:11600-11605(1993).\u003cbr\u003eCharles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NOS2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience?Cancer;Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484030972004,"sku":"CSB-PA178152","price":621.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_8117814a-d3ca-4657-92bd-bb3d26f4fa66.jpg?v=1660086480","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/phospho-nos2-tyr151-antibody-cat-csb-pa178152","provider":"GeneBio ","version":"1.0","type":"link"}