{"product_id":"phospho-ncf1-ser304-antibody-cat-csb-pa910023","title":"Phospho-NCF1 (Ser304) Antibody - Cat. #: CSB-PA910023","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:47 kDa autosomal chronic granulomatous disease protein antibody; 47 kDa neutrophil oxidase factor antibody; NADPH oxidase organizer 2 antibody; NCF 47K antibody; NCF-1 antibody; NCF-47K antibody; Ncf1 antibody; NCF1_HUMAN antibody; Neutrophil cytosol factor 1 antibody; Neutrophil cytosolic factor 1 antibody; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) antibody; Neutrophil NADPH oxidase factor 1 antibody; Nox organizer 2 antibody; Nox organizing protein 2 antibody; Nox-organizing protein 2 antibody; NOXO2 antibody; p47 phox antibody; p47-phox antibody; SH3 and PX domain containing protein 1A antibody; SH3 and PX domain-containing protein 1A antibody; SH3PXD1A antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P14598\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of Serine 304(R-S-S(p)-I-R) derived from Human Neutrophil Cytosol Factor 1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eNCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).\u003cbr\u003e\u003cbr\u003eRodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).\u003cbr\u003eGorlach A., J. Clin. Invest. 100:1907-1918(1997).\u003cbr\u003eChanock S.J., Blood Cells Mol. Dis. 26:37-46(2000)\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NCF1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484029562980,"sku":"CSB-PA910023","price":621.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_0fd024d1-5afa-4173-b5c7-d3b82dd3c7ed.jpg?v=1660086437","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/phospho-ncf1-ser304-antibody-cat-csb-pa910023","provider":"GeneBio ","version":"1.0","type":"link"}