{"product_id":"phospho-gja1-ser265-antibody-cat-csb-pa069474","title":"Phospho-GJA1 (Ser265) Antibody - Cat. #: CSB-PA069474","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Connexin 43 antibody; Connexin-43 antibody; Cx 43 antibody; Cx43 antibody; CXA1_HUMAN antibody; DFNB38 antibody; Gap junction 43 kDa heart protein antibody; Gap junction alpha-1 protein antibody; Gap junction protein alpha 1 43kDa (connexin 43) antibody; Gap junction protein alpha 1 43kDa antibody; Gap junction protein alpha like antibody; GJA 1 antibody; Gja1 antibody; GJAL antibody; ODD antibody; ODDD antibody; ODOD antibody; SDTY3 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P17302\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of Serine 265(Q-K-Y(p)-A-Y) derived from Human Connexin 43.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eOne gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.\u003cbr\u003e\u003cbr\u003eToshihiko Toyofuku, J. Biol. Chem., May 1998; 273: 12725.\u003cbr\u003eToshihiko Toyofuku, J. Biol. Chem., Jan 1998; 273: 1519.\u003cbr\u003eMasayuki Shimada, Biol Reprod, Apr 2001; 64: 1255.\u003cbr\u003eMerry L. Lindsey, Circulation, Jun 2006; 113: 2919 - 2928.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:GJA1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cardiovascular;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484031004772,"sku":"CSB-PA069474","price":621.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_43438d7e-33df-48f9-9cf2-914d3157b4e5.jpg?v=1660086481","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/phospho-gja1-ser265-antibody-cat-csb-pa069474","provider":"GeneBio ","version":"1.0","type":"link"}