{"product_id":"nxf1-antibody-cat-csb-pa260303","title":"NXF1 Antibody - Cat. #: CSB-PA260303","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:DKFZp667O0311 antibody; DmNXF1 antibody; MEX67 antibody; MEX67, yeast, homolog of antibody; Mex67p antibody; mRNA export factor TAP antibody; Mvb1 antibody; Nuclear RNA export factor 1 antibody; Nuclear RNA export factor 1 homolog (S. cerevisiae) antibody; nxf 1 antibody; NXF1 antibody; NXF1_HUMAN antibody; Protein small bristles antibody; Sbr antibody; TAP antibody; Tip associating protein antibody; Tip-associated protein antibody; Tip-associating protein antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9UBU9\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from N-terminal of Human NXF1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP\/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF\/THOC4 and THOC5 components of the TREX complex. ALYREF\/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.\u003cbr\u003e\u003cbr\u003eBraun I.C., EMBO J. 18:1953-1965(1999).\u003cbr\u003eKang Y., Genes Dev. 13:1126-1139(1999).\u003cbr\u003eBear J., Mol. Cell. Biol. 19:6306-6317(1999).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NXF1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Tags \u0026amp; Cell Markers\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483717382244,"sku":"CSB-PA260303","price":513.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_7d91f18e-b5db-469d-9328-9dc5b8c27f0a.jpg?v=1660074589","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/nxf1-antibody-cat-csb-pa260303","provider":"GeneBio ","version":"1.0","type":"link"}