{"product_id":"nkx3-1-antibody-cat-csb-pa143729","title":"NKX3-1 Antibody - Cat. #: CSB-PA143729","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:BAPX 2 antibody; BAPX2 antibody; Homeobox protein NK-3 homolog A antibody; Homeobox protein Nkx 3.1 antibody; Homeobox protein Nkx-3.1 antibody; Homeobox protein Nkx3.1 antibody; NK homeobox (Drosophila) family 3 A antibody; NK homeobox family 3 A antibody; NK homeobox, family 3, member A antibody; NK3 homeobox 1 antibody; NK3 transcription factor homolog A antibody; NK3 transcription factor related locus 1 antibody; NKX 3 antibody; Nkx 3.1 antibody; NKX 3A antibody; NKX3 1 antibody; NKX3 antibody; Nkx3-1 antibody; NKX3.1 antibody; Nkx3.1, mouse, homolog of antibody; NKX31_HUMAN antibody; NKX3A antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q99801\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from N-terminal of Human NKX3.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.\u003cbr\u003e\u003cbr\u003eCai Bowen, Cancer Res., Jan 2007; 67: 455 - 464. \u003cbr\u003eXiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017. \u003cbr\u003eEkatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173. \u003cbr\u003eCarlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690. \u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NKX3-1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483697590372,"sku":"CSB-PA143729","price":513.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_c78ec332-1e3e-433f-89da-926a03ef0d6a.jpg?v=1660074121","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/nkx3-1-antibody-cat-csb-pa143729","provider":"GeneBio ","version":"1.0","type":"link"}