{"product_id":"mre11a-antibody-cat-csb-pa620425","title":"MRE11A Antibody - Cat. #: CSB-PA620425","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AT like disease antibody; Ataxia telangiectasia disorder like antibody; ATLD antibody; DNA recombination and repair protein antibody; Double strand break repair protein MRE11A antibody; Double-strand break repair protein MRE11A antibody; endo\/exonuclease Mre11 antibody; HNGS1 antibody; meiotic recombination (S. cerevisiae) 11 homolog A antibody; Meiotic recombination 11 homolog 1 antibody; meiotic recombination 11 homolog A (S. cerevisiae) antibody; Meiotic recombination 11 homolog A antibody; MmMRE11A antibody; Mre 11 antibody; MRE 11a antibody; MRE 11b antibody; MRE11 homolog 1 antibody; MRE11 homolog A antibody; MRE11 homolog double strand break repair nuclease antibody; MRE11 meiotic recombination 11 homolog A (S. cerevisiae) antibody; MRE11 meiotic recombination 11 homolog A antibody; MRE11_HUMAN antibody; MRE11A antibody; MRE11b antibody; OTTHUMP00000236830 antibody; OTTHUMP00000236831 antibody; OTTHUMP00000236832 antibody; OTTHUMP00000236833 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P49959\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthetic peptide of Human MRE11A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:20-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:MRE11\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483601940580,"sku":"CSB-PA620425","price":287.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_fc4056c7-e5c9-42bf-990c-87838e8722fd.jpg?v=1660072088","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/mre11a-antibody-cat-csb-pa620425","provider":"GeneBio ","version":"1.0","type":"link"}