{"product_id":"kdm5c-antibody-hrp-conjugated-cat-csb-pa011939hb01hu","title":"KDM5C Antibody, HRP conjugated - Cat. #: CSB-PA011939HB01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:DXS1272E antibody; Histone demethylase JARID1C antibody; JARID1C antibody; JmjC domain containing protein SMCX antibody; Jumonji AT rich interactive domain 1C antibody; Jumonji, AT rich interactive domain 1C (RBP2 like) antibody; Jumonji\/ARID domain-containing protein 1C antibody; KDM5C antibody; KDM5C_HUMAN antibody; Lysine (K) specific demethylase 5C antibody; Lysine-specific demethylase 5C antibody; MRX13 antibody; MRXJ antibody; MRXSCJ antibody; MRXSJ antibody; Protein SmcX antibody; Protein Xe169 antibody; rbp2 like protein antibody; Selected cDNA on X antibody; SMCX antibody; Smcx homolog X chromosome antibody; SmcX protein antibody; Smcy homolog X linked antibody; XE169 antibody; Xe169 protein antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P41229\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Lysine-specific demethylase 5C protein (45-324AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Histone demethylase that specifically demethylates \\'Lys-4\\' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \\'Lys-9\\', H3 \\'Lys-27\\', H3 \\'Lys-36\\', H3 \\'Lys-79\\' or H4 \\'Lys-20\\'. Demethylates trimethylated and dimethylated but not monomethylated H3 \\'Lys-4\\'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL\/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:HRP\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KDM5C\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486295142500,"sku":"CSB-PA011939HB01HU","price":292.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_25fcfc4a-1605-45dd-98a4-4d6ac79ae983.jpg?v=1660144343","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/kdm5c-antibody-hrp-conjugated-cat-csb-pa011939hb01hu","provider":"GeneBio ","version":"1.0","type":"link"}