{"product_id":"kat7-antibody-cat-csb-pa980473","title":"KAT7 Antibody - Cat. #: CSB-PA980473","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Hbo 1 antibody; HBO1 antibody; HBOa antibody; Histone acetyltransferase binding to hORC1 antibody; Histone acetyltransferase binding to ORC1 antibody; Histone acetyltransferase KAT7 antibody; Histone acetyltransferase MYST2 antibody; K(lysine) acetyltransferase 7 antibody; KAT 7 antibody; KAT7 antibody; Lysine acetyltransferase 7 antibody; MOZ antibody; MOZ YBF2\/SAS3 SAS2 and TIP60 protein antibody; MOZ, YBF2\/SAS3, SAS2 and TIP60 protein 2 antibody; MYST 2 antibody; MYST histone acetyltransferase 2 antibody; MYST protein 2 antibody; MYST-2 antibody; MYST2 antibody; MYST2_HUMAN antibody; SAS 2 antibody; SAS2 and TIP60 protein 2 antibody; TIP60 protein 2 antibody; YBF2\/SAS3 antibody; ZC2HC7 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:O95251\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human MYST2.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.\u003cbr\u003e\u003cbr\u003eIizuka M., J. Biol. Chem. 274:23027-23034(1999).\u003cbr\u003eSharma M., J. Biol. Chem. 275:35200-35208(2000).\u003cbr\u003eOlsen J.V., Cell 127:635-648(2006).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KAT7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483974938724,"sku":"CSB-PA980473","price":511.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_3875c60b-b6f7-483e-88f3-e454148b29e0.jpg?v=1660085092","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/kat7-antibody-cat-csb-pa980473","provider":"GeneBio ","version":"1.0","type":"link"}