{"product_id":"invivomab-anti-human-cd40-tnfrsf5-antibody-iv0136","title":"InVivoMAb Anti-Human CD40\/TNFRSF5 Antibody (Iv0136)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDescription\u003c\/b\u003e:Iv0136 is a bispecific, humanized monoclonal antibody engineered for cancer immunotherapy. It simultaneously targets CD40 and 4-1BB (CD137), enabling coordinated activation of antigen-presenting cells and T cells to enhance anti-tumor immune responses. By engaging these two pathways, Iv0136 is being investigated for its potential to modulate immune activity in both oncology and autoimmune research settings. Preclinical studies indicate that dual CD40\/4-1BB targeting may promote tumor control and influence immune regulation in models of diseases such as rheumatoid arthritis and multiple sclerosis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost species\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage buffer\u003c\/b\u003e:0.01M PBS, pH 7.4.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;95% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG1, kappa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA, Neutralization\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e:Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin level\u003c\/b\u003e:Please contact us for this information.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:P25942\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStability and Storage\u003c\/b\u003e:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:Iv0136\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Usage Information\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePredicted molecular weight\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote\u003c\/b\u003e:For research use only. Not suitable for clinical or therapeutic use.\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48672673529956,"sku":"HB782010","price":454.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_186c9831-368f-4a2f-a0e6-172f89368ae4.jpg?v=1782933376","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/invivomab-anti-human-cd40-tnfrsf5-antibody-iv0136","provider":"GeneBio ","version":"1.0","type":"link"}