{"product_id":"il36rn-antibody-cat-csb-pa866201dsr1hu","title":"IL36RN Antibody - Cat. #: CSB-PA866201DSR1HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AI413231 antibody; Family of interleukin 1 delta antibody; FIL1 antibody; FIL1 delta antibody; FIL1(DELTA) antibody; FIL1D antibody; Fil1delta antibody; I36RA_HUMAN antibody; IL 1 delta antibody; IL 1 related protein 3 antibody; IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta) antibody; Il 1h3 antibody; IL 1HY1 antibody; IL 1L1 antibody; IL 1ra homolog antibody; IL 1ra homolog, IL1F5 (Canonical product IL 1F5a) antibody; IL 1RP3 antibody; IL-1 delta antibody; IL-1-related protein 3 antibody; IL-1F5 antibody; IL-1HY1 antibody; IL-1L1 antibody; IL-1ra homolog 1 antibody; IL-1RP3 antibody; IL1F5 antibody; IL1HY1 antibody; IL1L1 antibody; IL1RP3 antibody; IL36RA antibody; IL36RN antibody; Interleukin 1 delta antibody; Interleukin 1 family member 5 (delta) antibody; Interleukin 1 family member 5 antibody; Interleukin 1 HY1 antibody; Interleukin 1 like protein 1 antibody; Interleukin 1 receptor antagonist homolog 1 antibody; Interleukin 36 receptor antagonist antibody; Interleukin-1 delta antibody; Interleukin-1 family member 5 antibody; Interleukin-1 HY1 antibody; Interleukin-1 receptor antagonist homolog 1 antibody; Interleukin-1-like protein 1 antibody; Interleukin-36 receptor antagonist protein antibody; MGC29840 antibody; PSORP antibody; RP23-176J12.6 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9UBH0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Interleukin-36 receptor antagonist protein (1-155AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; Recommended dilution: IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:IL36RN\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486082347108,"sku":"CSB-PA866201DSR1HU","price":287.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_81332923-66e6-4e9b-8f66-19433a0d4073.jpg?v=1660140491","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/il36rn-antibody-cat-csb-pa866201dsr1hu","provider":"GeneBio ","version":"1.0","type":"link"}