{"product_id":"human-cd40-ligand-tnfsf5-cd40lg-elisa-kit-picokine-r","title":"Human CD40 Ligand\/TNFSF5\/CD40LG ELISA Kit PicoKine®","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e: 96 wells\/kit, with removable strips.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e: ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication Details\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene Name\u003c\/b\u003e: CD40LG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: Natural and recombinant human CD40L\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e: CD40 ligand (CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb\/IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e: Expression system for standard: E.coli; Immunogen sequence: E108-L261\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eContents\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eReconstitution\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eReference\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: P29965\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eCross Reactivity\u003c\/b\u003e: There is no detectable cross-reactivity with other relevant proteins.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003ePhospho_site\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved Molecular Weight\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eCalculated Molecular Weight\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e: 959\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein Name\u003c\/b\u003e: CD40 ligand\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene Full Name\u003c\/b\u003e: CD40 ligand\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e: CD154; CD40 L; CD40 ligand; CD40L; CD40L\/CD154; CD40LG; gp39; hCD40L; HIGM1; IGM; IMD3; T BAM; T cell antigen Gp39; TNF related activation protein; TNFSF5; TRAP\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48788478132324,"sku":"EK0573","price":582.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_9b0413d0-efd8-4ba2-ac38-9d5a5e8b96bb.jpg?v=1784414289","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/human-cd40-ligand-tnfsf5-cd40lg-elisa-kit-picokine-r","provider":"GeneBio ","version":"1.0","type":"link"}