{"product_id":"hsd17b8-antibody-cat-csb-pa588793","title":"HSD17B8 Antibody - Cat. #: CSB-PA588793","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:17 beta HSD 8 antibody; 17 beta hydroxysteroid dehydrogenase 8 antibody; 17-beta-HSD 8 antibody; 17-beta-hydroxysteroid dehydrogenase 8 antibody; 17-beta-hydroxysteroid dehydrogenase VIII antibody; 3-oxoacyl-[acyl-carrier-protein] reductase antibody; 3-oxoacyl-acyl-carrier protein reductase, E. coli, homolog of antibody; Beta ketoacyl [acyl carrier protein] reductase like antibody; D6S2245E antibody; DHB8_HUMAN antibody; dJ1033B10.9 antibody; Estradiol 17 beta dehydrogenase 8 antibody; Estradiol 17-beta-dehydrogenase 8 antibody; Estrogen 17 oxidoreductase antibody; FABG antibody; FabG, E. coli, homolog of antibody; FabG-like antibody; FABGL antibody; H2 KE6 antibody; H2-KE6 antibody; HKE6 antibody; HSD17B8 antibody; Hydroxysteroid (17 beta) dehydrogenase 8 antibody; Ke-6 antibody; KE6 antibody; KE6, mouse homolog of antibody; Protein Ke6 antibody; Really interesting new gene 2 protein antibody; RING2 antibody; SDR30C1 antibody; Short chain dehydrogenase\/reductase family 30C member 1 antibody; Testosterone 17 beta dehydrogenase 8 antibody; Testosterone 17-beta-dehydrogenase 8 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q92506\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human HSD17B8\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:HSD17B8\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482913812580,"sku":"CSB-PA588793","price":292.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_1604b2e6-c6c5-4d51-8460-d72db56b1a79.jpg?v=1660059403","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/hsd17b8-antibody-cat-csb-pa588793","provider":"GeneBio ","version":"1.0","type":"link"}