{"product_id":"hsd17b10-antibody-cat-csb-pa860776ha01hu","title":"HSD17B10 Antibody - Cat. #: CSB-PA860776HA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:17 beta hydroxysteroid dehydrogenase 10 antibody; 17 beta hydroxysteroid dehydrogenase type 10 antibody; 17-beta-HSD 10 antibody; 17-beta-hydroxysteroid dehydrogenase 10 antibody; 17b HSD10 antibody; 3 hydroxy 2 methylbutyryl CoA dehydrogenase antibody; 3 hydroxyacyl CoA dehydrogenase type 2 antibody; 3 hydroxyacyl CoA dehydrogenase type II antibody; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody; 3-hydroxyacyl-CoA dehydrogenase type II antibody; 3-hydroxyacyl-CoA dehydrogenase type-2 antibody; AB binding alcohol dehydrogenase antibody; ABAD antibody; Ads9 antibody; Amyloid beta binding polypeptide antibody; Amyloid beta peptide binding alcohol dehydrogenase antibody; Amyloid beta peptide binding protein antibody; Amyloid beta peptide binding protein antibody; CAMR antibody; DUPXp11.22 antibody; Endoplasmic Reticulum Amyloid Binding Protein antibody; Endoplasmic reticulum associated amyloid beta peptide binding protein antibody; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody; ER associated amyloid beta-binding protein antibody; ERAB antibody; HADH 2 antibody; HADH2 antibody; HCD 2 antibody; HCD2 antibody; HCD2_HUMAN antibody; Hsd17b10 antibody; Hydroxyacyl CoA Dehydrogenase type II antibody; Hydroxyacyl Coenzyme A dehydrogenase type II antibody; Hydroxysteroid (17 beta) dehydrogenase 10 antibody; Mental retardation X linked syndromic 11 antibody; MHBD antibody; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase antibody; Mitochondrial ribonuclease P protein 2 antibody; Mitochondrial RNase P protein 2 antibody; MRPP2 antibody; MRX17 antibody; SCHAD antibody; SDR5C1 antibody; Short chain dehydrogenase\/reductase family 5C member 1 antibody; Short chain L 3 hydroxyacyl CoA dehydrogenase type 2 antibody; Short chain type dehydrogenase\/reductase XH98G2 antibody; Short-chain type dehydrogenase\/reductase XH98G2 antibody; Type 10 17b HSD antibody; Type 10 17beta hydroxysteroid dehydrogenase antibody; Type II HADH antibody; XH98G2 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q99714\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human 3-hydroxyacyl-CoA dehydrogenase type-2 protein (2-261AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IF, IP; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200, IP:1:200-1:2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1\/TRMT10C, MRPP2\/HSD17B10 and MRPP3\/KIAA0391, which cleaves tRNA molecules in their 5\\\\\\'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:HSD17B10\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience; Tags \u0026amp; Cell Markers; Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40485763645540,"sku":"CSB-PA860776HA01HU","price":287.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_378b853b-b797-4add-b3d8-6515026d01f7.jpg?v=1660135289","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/hsd17b10-antibody-cat-csb-pa860776ha01hu","provider":"GeneBio ","version":"1.0","type":"link"}