{"product_id":"cav1-antibody-cat-csb-pa870052","title":"CAV1 Antibody - Cat. #: CSB-PA870052","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:BSCL3 antibody; CAV antibody; CAV1 antibody; CAV1_HUMAN antibody; caveolae protein, 22 kD antibody; caveolin 1 alpha isoform antibody; caveolin 1 beta isoform antibody; Caveolin 1 caveolae protein 22kDa antibody; Caveolin-1 antibody; Caveolin1 antibody; cell growth-inhibiting protein 32 antibody; CGL3 antibody; LCCNS antibody; MSTP085 antibody; OTTHUMP00000025031 antibody; PPH3 antibody; VIP 21 antibody; VIP21 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q03135\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from Human Caveolin-1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor\/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.\u003cbr\u003e\u003cbr\u003eWei Zhang, J. Biol. Chem., Jun 2000; 275: 20717.\u003cbr\u003eRosalia Mora, J. Biol. Chem., Sep 1999; 274: 25708.\u003cbr\u003eIsabella Parolini, J. Biol. Chem., Sep 1999; 274: 25718.\u003cbr\u003ePhuong U. Le, J. Biol. Chem., Jan 2002; 277: 3371 - 3379.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CAV1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer?Cardiovascular;Tags \u0026amp; Cell Markers;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483998695524,"sku":"CSB-PA870052","price":508.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_c8d7be0f-d036-4c6a-8515-ad144788eb66.jpg?v=1660085767","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/cav1-antibody-cat-csb-pa870052","provider":"GeneBio ","version":"1.0","type":"link"}