{"product_id":"cacna1c-antibody-cat-csb-pa145166","title":"CACNA1C Antibody - Cat. #: CSB-PA145166","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:alpha-1 polypeptide antibody; cardiac muscle antibody; isoform 1 antibody; L type antibody; CAC1C_HUMAN antibody; CACH 2 antibody; CACH2 antibody; CACN 2 antibody; CACN2 antibody; CACNA1C antibody; CACNL1A1 antibody; Calcium channel antibody; Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody; Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody; Calcium channel voltage dependent L type alpha 1C subunit antibody; CaV1.2 antibody; CCHL1A1 antibody; DHPR alpha 1 antibody; DHPR alpha 1 subunit antibody; LQT8 antibody; TS antibody; Voltage dependent L type calcium channel alpha 1C subunit antibody; Voltage dependent L type calcium channel subunit alpha 1C antibody; Voltage gated calcium channel alpha subunit Cav1.2 antibody; Voltage gated calcium channel subunit alpha Cav1.2 antibody; Voltage gated L type calcium channel Cav1.2 alpha 1 subunit; splice variant 10* antibody; Voltage-dependent L-type calcium channel subunit alpha-1C antibody; Voltage-gated calcium channel subunit alpha Cav1.2 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q13936\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthetic peptide of Human CACNA1C\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2\/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CACNA1C\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience?Cancer?Cardiovascular;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483562094692,"sku":"CSB-PA145166","price":287.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_fa21247b-021e-40fc-8b1e-2a37a9813fe5.jpg?v=1660071071","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/cacna1c-antibody-cat-csb-pa145166","provider":"GeneBio ","version":"1.0","type":"link"}