{"product_id":"af-le-purified-anti-human-cd86-antibody-it2-2","title":"AF\/LE Purified Anti-Human CD86 Antibody[IT2.2]","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:1mg\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze \/ thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:Ice bag\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Primary Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Flow Cytometry Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbbreviation\u003c\/b\u003e:CD86\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Synonym\u003c\/b\u003e:LAB;ETC;FUN;CTLA-4 Counter-Receptor B;Early T-cell costimulatory molecule;CD28LG;B7-2;B7.2;B70;CD28LG2;LAB72;CD86;Activation B7-2 antigen;BU63;CTLA-4 Counter-Receptor B7.2;Early T-cell costimulatory molecule 1;ETC-1;FUN-1;T-lymphocyte activation antigen CD86; B7-2;Activation B7-2 antigen 3;B7 2;B72 antigen;B-lymphocyte activation antigen B7-2;B-lymphocyte activation antigen B7-2 2;CD28 antigen ligand 2;CD28 antigen ligand 2 2;Cd28l2;CD86 antigen;CD86 molecule;CLS1;CTLA-4 counter-receptor B7.2 2;FUN 1;Ly58;Ly-58;MB7;MB7-2;Membrane glycoprotein;MGC34413;TS\/A-2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology;Microbiology;Stem Cells;Kits;Lysates;Other\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:None (AF\/LE)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:FCM\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUsage\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:Mouse IgG2b, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone NO.\u003c\/b\u003e:IT2.2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUNIProt ID\u003c\/b\u003e:P42081\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e: ≥ 1 mg\/mL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eControl catalog number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human CD86 protein\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Sterile PBS, pH 7.2. \u0026lt; 1.0 EU per mg of the antibody as determined by the LAL method.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification method\u003c\/b\u003e:\u0026gt;98%, Protein A\/G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:FCM 2 μg\/mL(0.5×10\u003csup\u003e6\u003c\/sup\u003e-1×10\u003csup\u003e6\u003c\/sup\u003e cells)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGeneID\u003c\/b\u003e:942\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48654393442404,"sku":"GBS-F12690","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_bfdf38da-f15d-4574-852f-460fcfa1973e.jpg?v=1782787904","url":"https:\/\/www.genebiosystems.com\/en-gb\/products\/af-le-purified-anti-human-cd86-antibody-it2-2","provider":"GeneBio ","version":"1.0","type":"link"}