{"product_id":"vav1-ab-174-antibody-cat-csb-pa918051","title":"VAV1 (Ab-174) Antibody - Cat. #: CSB-PA918051","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Oncogene vav antibody; p95Vav antibody; Proto-oncogene vav antibody; Protooncogene vav antibody; VAV 1 antibody; VAV 1 oncogene antibody; VAV antibody; Vav proto oncogene antibody; VAV_HUMAN antibody; VAV1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P15498\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized non-phosphopeptide derived from Human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Couples tyrosine kinase signals with the activation of the Rho\/Rac GTPases, thus leading to cell differentiation and\/or proliferation.\u003cbr\u003e\u003cbr\u003eAna V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 - 38265.\u003cbr\u003eChristopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 - 6299.\u003cbr\u003eVered Schapira, Cancer Res., Jun 2006; 66: 6183 - 6191.\u003cbr\u003eMaya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 - 50130.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:VAV1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483788587108,"sku":"CSB-PA918051","price":597.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_a34b9b03-0281-4fbf-9871-d33aab67c1ae.jpg?v=1660076274","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/vav1-ab-174-antibody-cat-csb-pa918051","provider":"GeneBio ","version":"1.0","type":"link"}