{"product_id":"tyk2-phospho-tyr1054-1055-rabbit-polyclonal-antibody-ab","title":"Tyk2(Phospho-Tyr1054\/1055) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100μL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such| it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch_area\u003c\/b\u003e:Signal transduction; Microbiology\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget_protein\u003c\/b\u003e:TYK2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eapplications\u003c\/b\u003e:WB\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e:Human, Rat, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene Symbol\/ Name\u003c\/b\u003e:Tyk2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:-20°C for 1 year\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:1 mg\/ml\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMolecular weight(Da)\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt accession\u003c\/b\u003e:Human: P29597; Mouse: Q9R117\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e:Tyk2 ;Tyr1054\/1055 ; Non-receptor tyrosine-protein kinase TYK2; EC 2.7.10.2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGeneID\u003c\/b\u003e:Human: 7297\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48650332110948,"sku":"BT-AP13304","price":470.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_39cd1d59-f59c-4cbc-ab53-fdc33abb6f08.jpg?v=1782733331","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/tyk2-phospho-tyr1054-1055-rabbit-polyclonal-antibody-ab","provider":"GeneBio ","version":"1.0","type":"link"}