{"product_id":"tead4-antibody-biotin-conjugated-cat-csb-pa618010ld01hu","title":"TEAD4 Antibody, Biotin conjugated - Cat. #: CSB-PA618010LD01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:EFTR 2 antibody; EFTR2 antibody; hRTEF 1B antibody; hRTEF1B antibody; MGC9014 antibody; OTTHUMP00000238119 antibody; OTTHUMP00000238122 antibody; OTTHUMP00000238124 antibody; Related to TEF 1 antibody; Related to TEF1 antibody; Related transcription enhancer factor 1B antibody; RTEF1 antibody; TCF13L1 antibody; TEA domain family member 4 antibody; TEAD 4 antibody; TEAD-4 antibody; TEAD4 antibody; TEAD4_HUMAN antibody; TEF 3 antibody; TEF3 antibody; TEFR 1 antibody; TEFR1 antibody; Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody; Transcription factor 13 like 1 antibody; Transcription factor 13-like 1 antibody; Transcription factor RTEF 1 antibody; Transcription factor RTEF-1 antibody; Transcription factor RTEF1 antibody; Transcriptional enhancer factor 1 related antibody; Transcriptional enhancer factor 3 antibody; Transcriptional enhancer factor TEF 3 antibody; Transcriptional enhancer factor TEF-3 antibody; Transcriptional enhancer factor TEF3 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q15561\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1\/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1\/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1\/TAZ. Acts by mediating gene expression of YAP1 and WWTR1\/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC \\'enhansons\\' (5\\'-GTGGAATGT-3\\') and activates transcription. Binds to the M-CAT motif.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Biotin\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:TEAD4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Cardiovascular\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40485058543716,"sku":"CSB-PA618010LD01HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_3ce2216f-42fb-4435-9418-a87cc494a857.jpg?v=1660111513","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/tead4-antibody-biotin-conjugated-cat-csb-pa618010ld01hu","provider":"GeneBio ","version":"1.0","type":"link"}