{"product_id":"rrm2b-antibody-cat-csb-pa277130","title":"RRM2B Antibody - Cat. #: CSB-PA277130","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:DKFZp686M05248 antibody; MGC102856 antibody; MGC42116 antibody; MTDPS8A antibody; MTDPS8B antibody; p53 inducible ribonucleotide reductase small subunit 2 homolog antibody; p53 inducible ribonucleotide reductase small subunit 2 like protein antibody; P53 inducible ribonucleotide reductase small subunit 2 short form beta antibody; p53 R2 antibody; p53-inducible ribonucleotide reductase small subunit 2-like protein antibody; p53R2 antibody; Ribonucleoside diphosphate reductase M2 subunit B antibody; Ribonucleoside-diphosphate reductase subunit M2 B antibody; Ribonucleotide reductase M2 B (TP53 inducible) antibody; Ribonucleotide reductase M2 B antibody; Ribonucleotide reductase small subunit like 2 p53 inducible antibody; RIR2B_HUMAN antibody; RRM 2B antibody; RRM2B antibody; TP53 inducible ribonucleotide reductase M2 B antibody; TP53-inducible ribonucleotide reductase M2 B antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q7LG56\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from Internal of Human RRM2B.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Plays a pivotal role in cell survival by repairing damaged DNA in a p53\/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.\u003cbr\u003e\u003cbr\u003eTanaka H., Nature 404:42-49(2000).\u003cbr\u003eUgai H., Submitted (MAR-2004) to the EMBL\/GenBank\/DDBJ databases.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RRM2B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483771547748,"sku":"CSB-PA277130","price":597.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_55a173ca-c00a-41b0-a404-2d9cee22954f.jpg?v=1660075893","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/rrm2b-antibody-cat-csb-pa277130","provider":"GeneBio ","version":"1.0","type":"link"}