{"product_id":"rassf5-antibody-cat-csb-pa819906esr1hu","title":"RASSF5 Antibody - Cat. #: CSB-PA819906ESR1HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Maxp 1 antibody; MAXP1 antibody; MGC10823 antibody; MGC17344 antibody; New ras effector 1 antibody; NORE 1 antibody; NORE1 antibody; NORE1A antibody; NORE1B antibody; Novel Ras effector 1 antibody; RAP1 Binding Protein antibody; RAPL antibody; Ras association (RalGDS\/AF 6) domain family 5 antibody; Ras association (RalGDS\/AF 6) domain family member 5 antibody; Ras association domain containing family protein 5 antibody; Ras association domain-containing protein 5 antibody; Ras effector like protein antibody; RASF5_HUMAN antibody; RASSF 3 antibody; RASSF 5 antibody; RASSF3 antibody; RASSF5 antibody; Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody; Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody; Tumor suppressor RASSF3 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q8WWW0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL\/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4\/MST1 complex may mediate HRAS and KRAS induced apoptosis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RASSF5\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer; Cell biology; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486151061604,"sku":"CSB-PA819906ESR1HU","price":332.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_035f4989-f4a1-47ec-b55c-acc80c5ea64b.jpg?v=1660141556","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/rassf5-antibody-cat-csb-pa819906esr1hu","provider":"GeneBio ","version":"1.0","type":"link"}