{"product_id":"ptgs2-antibody-cat-csb-pa018986la01hu","title":"PTGS2 Antibody - Cat. #: CSB-PA018986LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:COX 2 antibody; COX-2 antibody; COX2 antibody; Cyclooxygenase 2 antibody; Cyclooxygenase 2b antibody; Cyclooxygenase antibody; Cyclooxygenase-2 antibody; Cyclooxygenase2 antibody; EC 1.14.99.1 antibody; fj02a10 antibody; Glucocorticoid-regulated inflammatory cyclooxygenase antibody; Glucocorticoid-regulated inflammatory Prostaglandin G\/H synthase antibody; GRIPGHS antibody; hCox 2 antibody; Macrophage activation-associated marker protein P71\/73 antibody; OTTHUMP00000033524 antibody; PES-2 antibody; PGG\/HS antibody; PGH synthase 2 antibody; PGH2_HUMAN antibody; PGHS 2 antibody; PGHS-2 antibody; PGHS2 antibody; PHS 2 antibody; PHS II antibody; PHS2 antibody; Prostaglandin endoperoxide synthase 2 (prostaglandin G\/H synthase and cyclooxygenase) antibody; Prostaglandin endoperoxide synthase 2 antibody; Prostaglandin G\/H synthase 2 antibody; Prostaglandin G\/H synthase 2 precursor antibody; Prostaglandin G\/H synthase and cyclooxygenase antibody; Prostaglandin G\/H synthase antibody; Prostaglandin H2 synthase 2 antibody; prostaglandin-endoperoxide synthase 2 (prostaglandin G\/H synthase and cyclooxygenase) antibody; Prostaglandin-endoperoxide synthase 2 antibody; PTGS2 antibody; ptgs2a antibody; TIS10 antibody; TIS10 protein antibody; unp1239 antibody; wu:fj02a10 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P35354\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Prostaglandin G\/H synthase 2 protein (18-268AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; Recommended dilution: WB:1:500-1:2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PTGS2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer; Cardiovascular; Metabolism; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487798997092,"sku":"CSB-PA018986LA01HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_e4f46307-9e36-467e-9252-2846ec6810a3.jpg?v=1660171461","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/ptgs2-antibody-cat-csb-pa018986la01hu","provider":"GeneBio ","version":"1.0","type":"link"}