{"product_id":"ppm1d-antibody-cat-csb-pa018491esr2hu","title":"PPM1D Antibody - Cat. #: CSB-PA018491ESR2HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:EC 3.1.3.16 antibody; p53 induced protein phosphatase 1 antibody; p53-induced protein phosphatase 1 antibody; PP2C delta antibody; PP2C-delta antibody; PP2CD antibody; Ppm1d antibody; PPM1D_HUMAN antibody; Protein phosphatase 1D antibody; protein phosphatase 1D magnesium-dependent delta isoform antibody; Protein phosphatase 2C delta isoform antibody; Protein phosphatase 2C isoform delta antibody; Protein phosphatase magnesium dependent 1 delta antibody; Protein phosphatase magnesium-dependent 1 delta antibody; Protein phosphatase Mg2+\/Mn2+ dependent 1D antibody; Protein phosphatase Wip1 antibody; Wild type p53 induced phosphatase 1 antibody; WIP 1 antibody; WIP1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:O15297\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Protein phosphatase 1D protein (1-250AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates \\\\\\'Ser-15\\\\\\' of TP53 and \\\\\\'Ser-345\\\\\\' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PPM1D\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486125600868,"sku":"CSB-PA018491ESR2HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_4c3ade43-7712-4954-b7b3-e3237aac7903.jpg?v=1660141111","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/ppm1d-antibody-cat-csb-pa018491esr2hu","provider":"GeneBio ","version":"1.0","type":"link"}