{"product_id":"pe-fluor-r-594-anti-human-mouse-integrin-b7-antibody-fib21","title":"PE\/ Fluor® 594 Anti-Human\/Mouse Integrin β7 Antibody[FIB21]","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100Tests\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:Ice bag\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Primary Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Flow Cytometry Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbbreviation\u003c\/b\u003e:Integrin β7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Synonym\u003c\/b\u003e:β7 Integrin;integrin βp;ITGB7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:PE\/Elab Fluor®594\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human;Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:FCM\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUsage\u003c\/b\u003e:Each lot of this antibody is quality control tested by flow cytometric analysis. \u003cb style=\"color:#0070ca\"\u003eThe amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood).\u003c\/b\u003e Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:Rat IgG2b, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone NO.\u003c\/b\u003e:FIB21\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUNIProt ID\u003c\/b\u003e:P26010;P26011\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4\/β7 or αE\/β7 heterodimer. α4\/β7 (CD49d\/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE\/β7 (CD103\/β7,αIEL\/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103\/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:5 μL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eControl catalog number\u003c\/b\u003e:E-AB-F09842P\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification method\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGeneID\u003c\/b\u003e:3695;16421\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48654225178724,"sku":"AN00423P","price":433.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_197a31a8-1d69-4a3b-af0e-eebed08d3d22.jpg?v=1782783485","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/pe-fluor-r-594-anti-human-mouse-integrin-b7-antibody-fib21","provider":"GeneBio ","version":"1.0","type":"link"}