{"product_id":"pdzk1-antibody-cat-csb-pa722565ha01hu","title":"PDZK1 Antibody - Cat. #: CSB-PA722565HA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:1700023D20Rik antibody; 2610507N21Rik antibody; 4921513F16Rik antibody; AI267131 antibody; AI314638 antibody; AL022680 antibody; C terminal linking and modulating protein antibody; CAP70 antibody; CFTR associated protein of 70 kDa  antibody; CFTR associated protein; 70-KD antibody; CFTR-associated protein of 70 kDa antibody; CLAMP antibody; D3Ertd537e antibody; Dietary Pi-regulated RNA-1 antibody; Diphor-1 antibody; mPDZK1 antibody; Na(+)\/H(+) exchange regulatory cofactor NHE-RF3 antibody; Na(+)\/H(+) exchanger regulatory factor 3 antibody; Na\/Pi cotransporter C-terminal-associated protein 1 antibody; Na\/Pi cotransporter C-terminal-associated protein antibody; NaPi Cap1 antibody; NaPi-Cap1 antibody; NaPiCap1 antibody; NHERF 3 antibody; NHERF-3 antibody; NHERF3 antibody; NHRF3_HUMAN antibody; OTTHUMP00000015572  antibody; PDZ domain containing 1 antibody; PDZ domain containing protein 1 antibody; PDZ domain-containing protein 1 antibody; PDZD1 antibody; PDZK1 antibody; Sodium hydrogen exchanger regulatory factor 3 antibody; Sodium-hydrogen exchanger regulatory factor 3 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q5T2W1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Na(+)\/H(+) exchange regulatory cofactor NHE-RF3 protein (1-519AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PDZK1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer; Metabolism; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40485120442468,"sku":"CSB-PA722565HA01HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_7ad7a81d-5dea-4a3c-9a6c-5628893e1bd8.jpg?v=1660112891","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/pdzk1-antibody-cat-csb-pa722565ha01hu","provider":"GeneBio ","version":"1.0","type":"link"}