{"product_id":"mme-antibody-cat-csb-pa014653la01hu","title":"MME Antibody - Cat. #: CSB-PA014653LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Atriopeptidase antibody; CALLA antibody; CD10 antibody; CD10 antigen antibody; Common acute lymphocytic leukemia antigen antibody; DKFZp686O16152 antibody; EC 3.4.24.11 antibody; Enkephalinase antibody; EPN antibody; Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody; Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody; Membrane metallo endopeptidase antibody; Membrane metallo endopeptidase variant 1 antibody; Membrane metallo endopeptidase variant 2 antibody; Membrane metalloendopeptidase antibody; Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody; Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody; Membrane metalloendopeptidase variant 1 antibody; Membrane metalloendopeptidase variant 2 antibody; MGC126681 antibody; MGC126707 antibody; MME antibody; NEP antibody; NEP_HUMAN antibody; Neprilysin antibody; neprilysin-390 antibody; neprilysin-411 antibody; Neutral endopeptidase 24.11 antibody; Neutral endopeptidase antibody; Neutral endopeptidase, membrane-associated antibody; SFE antibody; Skin fibroblast elastase antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P08473\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Neprilysin protein (386-617AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; Recommended dilution: IHC:1:100-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:MME\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Signal Transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487891239012,"sku":"CSB-PA014653LA01HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_a6f9166c-2497-4b30-9ae3-aec88eaf12c1.jpg?v=1660172768","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/mme-antibody-cat-csb-pa014653la01hu","provider":"GeneBio ","version":"1.0","type":"link"}