{"product_id":"il1r2-antibody-cat-csb-pa011622esr1hu","title":"IL1R2 Antibody - Cat. #: CSB-PA011622ESR1HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:IL1 Receptor II  antibody; Antigen CDw121b antibody; CD121 antibody; CD121 antigen-like family member B antibody; CD121b antibody; CD121B Antigen antibody; CDw121b antibody; IL 1 type II receptor antibody; IL-1R-2 antibody; IL-1R-beta antibody; IL-1R2 antibody; IL-1RT-2 antibody; IL-1RT2 antibody; IL1R Beta antibody; Il1r-2 antibody; IL1R2 antibody; IL1R2_HUMAN antibody; IL1R2c antibody; IL1RB antibody; Interleukin 1 receptor type II variant 3 antibody; Interleukin 1 receptor; beta; type II antibody; Interleukin 1 receptor; type II antibody; Interleukin-1 receptor beta antibody; Interleukin-1 receptor type 2 antibody; Interleukin-1 receptor type II antibody; MGC137383 antibody; MGC47725 antibody; OTTHUMP00000207969 antibody; p68 antibody; Type II interleukin-1 receptor; beta antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P27930\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; Recommended dilution: WB:1:200-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted\/soluble receptors.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:IL1R2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cardiovascular; Immunology; Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486039027812,"sku":"CSB-PA011622ESR1HU","price":333.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_448159ad-1ddb-4dab-a2d4-f94d477739b2.jpg?v=1660139895","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/il1r2-antibody-cat-csb-pa011622esr1hu","provider":"GeneBio ","version":"1.0","type":"link"}