{"product_id":"hltf-antibody-fitc-conjugated-cat-csb-pa010520lc01hu","title":"HLTF Antibody, FITC conjugated - Cat. #: CSB-PA010520LC01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:DNA-binding protein\/plasminogen activator inhibitor 1 regulator antibody; Helicase like transcription factor antibody; Helicase-like transcription factor antibody; HIP116 antibody; HIP116A antibody; HLTF 1 antibody; Hltf antibody; HLTF_HUMAN antibody; HLTF1 antibody; p113 antibody; RING finger protein 80 antibody; RNF80 antibody; SMARC A3 antibody; SMARCA 3 antibody; SMARCA3 antibody; SNF2-like 3 antibody; SNF2L3 antibody; Sucrose nonfermenting protein 2 like 3 antibody; Sucrose nonfermenting protein 2-like 3 antibody; SWI\/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3 antibody; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin a3 antibody; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 antibody; ZBU 1 antibody; ZBU1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q14527\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Helicase-like transcription factor protein (332-476AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for \\'Lys-63\\'-linked polyubiquitination of chromatin-bound PCNA.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:FITC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:HLTF\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Cancer; Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487084261476,"sku":"CSB-PA010520LC01HU","price":334.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_1abed454-2963-43da-ad85-3312d369723c.jpg?v=1660158950","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/hltf-antibody-fitc-conjugated-cat-csb-pa010520lc01hu","provider":"GeneBio ","version":"1.0","type":"link"}