{"product_id":"gabrb1-ab-434-antibody-cat-csb-pa620050","title":"GABRB1 (Ab-434) Antibody - Cat. #: CSB-PA620050","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AW061132 antibody; B230208N19Rik antibody; GABA(A) receptor beta 1 antibody; GABA(A) receptor subunit beta-1 antibody; GABA-A receptor; beta-1 polypeptide antibody; Gabrb-1 antibody; GABRB1 antibody; Gamma aminobutyric acid (GABA) A receptor beta 1 antibody; Gamma Aminobutyric Acid A Receptor Beta 1 antibody; Gamma Aminobutyric Acid Receptor ; beta-1 antibody; Gamma-aminobutyric acid (GABA) A receptor; subunit beta 1 antibody; Gamma-aminobutyric acid receptor subunit beta-1 antibody; GARB1 antibody; GBRB1_HUMAN antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P18505\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.\u003cbr\u003e\u003cbr\u003eCollins AL, et al. (2006) Neurogenetics ;7(3):167-174.\u003cbr\u003eMa DQ, et al. (2005) Am J Hum Genet ;77(3):377-388.\u003cbr\u003eEdenberg HJ, et al. (2004) Am J Hum Genet ;74(4):705-714.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:GABRB1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience?Cancer;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483682320484,"sku":"CSB-PA620050","price":593.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_aad453d4-5aa5-4250-bb59-a58788a98c19.jpg?v=1660073766","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/gabrb1-ab-434-antibody-cat-csb-pa620050","provider":"GeneBio ","version":"1.0","type":"link"}