FOXO4 antibody , Cat. # FNab03203

SKU: FNab03203

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements(IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells(ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

Immunogen:forkhead box O4

Synonyms:AFX, AFX1, MLLT7

Observed MW:45-48kd

Uniprot ID:P98177

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID:4303

Research Area:Epigenetics, Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience