{"product_id":"cleaved-plasma-kallikrein-hc-r390-rabbit-pab-antibody","title":"Cleaved-Plasma Kallikrein HC (R390) rabbit pAb","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e: 100μL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSource\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:WB;IHC;IF;ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e:Human;Rat;Mouse;\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage_stability\u003c\/b\u003e:-20°C\/1 year\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:1 mg\/ml\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved_band(KD)\u003c\/b\u003e:45kD\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHuman_gene_id\u003c\/b\u003e:3818\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHuman_swiss_prot_no\u003c\/b\u003e:P03952\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSubcellular_location\u003c\/b\u003e:Secreted.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eOther_name\u003c\/b\u003e:KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48647069270116,"sku":"ES1072","price":325.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_81e431e5-6d45-4122-bdd0-3efc282072d0.jpg?v=1782687681","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/cleaved-plasma-kallikrein-hc-r390-rabbit-pab-antibody","provider":"GeneBio ","version":"1.0","type":"link"}